ea0063p874 | Adrenal and Neuroendocrine Tumours 3 | ECE2019
Gonzales Maria Santamaria
, Toro Jose Jorge Ortez
, Fernandez Elena Llorente
, Miranda Carlos Miguel Peteiro
Background: Multiple endocrine neoplasia type 1 (MEN1) (OMIM 131100) is an autosomal dominant disorder associated with a high risk of developing parathyroid hyperplasia (90%), digestive neuroendocrine tumors (3070%) and pituitary adenomas (30-40%). Prevalence of MEN1 is 2-10/100.000, there are no differences between men and women and usually, it is diagnosed before 40 years old. It is related to different mutations of the MEN1 tumour-suppressor gene (OMIM: 613733) which ...